Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301628 | 0.97 | ACHE (0.35) | PHGDHMGLLACHEALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7497886 | 0.95 | ACHE (0.34) | PHGDHMGLLACHEALDH1A1POLB | |
| Bromide SCHEMBL8688240 | 0.95 | ACHE (0.34) | PHGDHMGLLACHEALDH1A1POLB | |
| SCHEMBL727807 | 0.90 | ALDH1A1 (0.37) | PHGDHMGLLACHEALDH1A1LMNA | |
| SCHEMBL3446740 | 0.90 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7497872 | 0.87 | ALDH1A1 (0.38) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL10451712 | 0.87 | ALDH1A1 (0.38) | ACHEALDH1A1LMNAPOLBMEN1 | |
| Bromide SCHEMBL8688236 | 0.87 | ALDH1A1 (0.38) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL10982018 | 0.86 | ACHE (0.41) | PHGDHMGLLACHEALDH1A1POLB | |
| SCHEMBL8802556 | 0.83 | ACHE (0.44) | PHGDHMGLLACHEALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4763285-B2 | — | — | 2011-08-31 | — | — | JP | claimed |
| EP-1521781-B1 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | BRIDGESTONE CORP (JP) | 2009-03-25 | — | — | EP | claimed |
| US-7405262-B2 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2008-07-29 | — | — | US | claimed |
| US-20060036050-A1 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2006-02-16 | — | — | US | claimed |
| EP-1521781-A2 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | Bridgestone Corporation (JP) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007563-A2 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | BRIDGESTONE CORPORATION (JP) | 2004-01-22 | — | — | WO | claimed |
| US-9000070-B2 | Mixing of telechelic rubber formulations | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20130116360-A1 | MIXING OF TELECHELIC RUBBER FORMULATIONS | BRIDGESTONE CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| US-7671139-B1 | Functionalized polymers and tires made therefrom | BRIDGESTONE CORPORATION (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1521781-B1 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | BRIDGESTONE CORP (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-7405262-B2 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2008-07-29 | — | — | US | disclosed |
| US-20060036050-A1 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2006-02-16 | — | — | US | disclosed |
| EP-1521781-A2 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | Bridgestone Corporation (JP) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007563-A2 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | BRIDGESTONE CORPORATION (JP) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036050-A1 | Preparation of functionalized anionic polymerization initiators | PKD1, ALG8, ALG3 | PHGDH 3570/4885MGLL 2906/4885ACHE 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.