SCHEMBL7268115

SCHEMBL7268115

CCCC[C@H](NC(=O)[C@H](Cc1cccc2ccccc12)CS(=O)(=O)CC(COC(C)=O)OC(C)=O)C(=O)N[C@@H](CC(C)C)[C@@H](O)[C@@H](O)CSC(C)C

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7267565 0.92 REN (0.46) REN
SCHEMBL7278490 0.89 REN (0.52) REN
SCHEMBL7274986 0.84 HRH4 (0.44) REN
SCHEMBL7274988 0.84 HRH4 (0.44) REN
SCHEMBL7269350 0.81 CTSK (0.40) REN
SCHEMBL7269345 0.81 CTSK (0.40) REN
SCHEMBL7269214 0.79 REN (0.46) REN
SCHEMBL7278747 0.76 CTSK (0.39) REN
SCHEMBL7278741 0.76 CTSK (0.39) REN
SCHEMBL7267089 0.76 MMP2 (0.49) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377139-B1 N-substituted acylamino acid compounds, process for their production and their use BANYU PHARMA CO LTD (JP) 1995-07-12 — — EP claimed
US-5424309-A Hypotensive agents BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-06-13 — — US claimed
EP-0377139-A1 N-substituted acylamino acid compounds, process for their production and their use Banyu Pharmaceutical Co., Ltd. (JP) 1990-07-11 — — EP claimed
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