Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 5/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278135 | 0.85 | HRH4 (0.53) | MMP2MMP9MMP8MMEECE1 | |
| SCHEMBL7267914 | 0.85 | HRH4 (0.53) | MMP2MMP9MMP8MMEECE1 | |
| SCHEMBL7266079 | 0.81 | MME (0.47) | MMP2MMEECE1ACECPA1 | |
| SCHEMBL7280278 | 0.81 | MME (0.47) | MMP2MMEECE1ACECPA1 | |
| SCHEMBL7267230 | 0.80 | MME (0.48) | MMP2MMP9MMP8MMEECE1 | |
| SCHEMBL7276322 | 0.80 | REN (0.46) | MMP2MMP9MMP8 | |
| SCHEMBL7273054 | 0.80 | REN (0.46) | MMP2MMP9MMP8 | |
| SCHEMBL9083662 | 0.78 | HRH4 (0.50) | MMP2MMP9MMP8MMEECE1 | |
| SCHEMBL7266481 | 0.78 | MMP8 (0.55) | MMP2MMP9MMP8MME | |
| SCHEMBL7266488 | 0.78 | MMP8 (0.55) | MMP2MMP9MMP8MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309766-B1 | N-acylamino acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5506356-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| US-5481036-A | RENIN INHIBITORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5319082-A | N-acylamino acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5240924-A | Dipeptide hypotensives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| US-5122523-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |