Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266481 | 1.00 | MMP8 (0.55) | MMP8MMP2MMP9NTSR1MME | |
| SCHEMBL7268347 | 0.87 | MMP8 (0.51) | MMP8MMP2MMP9MMP1ADAM17 | |
| SCHEMBL7268353 | 0.87 | MMP8 (0.51) | MMP8MMP2MMP9MMP1ADAM17 | |
| SCHEMBL7268334 | 0.78 | MMP2 (0.46) | MMP8MMP2MMP9MME | |
| SCHEMBL10772819 | 0.73 | MMP2 (0.61) | MMP8MMP2MMP9MMEMMP1 | |
| SCHEMBL6622312 | 0.72 | MMP1 (0.52) | NTSR1MMP1ADAM17 | |
| SCHEMBL13957289 | 0.72 | MMP2 (0.50) | MMP8MMP2MMP9MMEHTR5A | |
| SCHEMBL20272582 | 0.72 | MMP2 (0.52) | MMP8MMP2MMP9HTR5A | |
| SCHEMBL5098994 | 0.71 | NTSR1 (0.58) | MMP2NTSR1MMP1ADAM17 | |
| SCHEMBL5099014 | 0.71 | NTSR1 (0.58) | MMP2NTSR1MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309766-B1 | N-acylamino acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5506356-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| US-5481036-A | RENIN INHIBITORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| US-5319082-A | N-acylamino acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5240924-A | Dipeptide hypotensives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| US-5122523-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |