Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782413 | 0.71 | CYP11B1 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL7259729 | 0.71 | CYP11B1 (0.61) | ALDH1A1CYP11B1CYP11B2IDH1 | |
| SCHEMBL31471987 | 0.69 | CYP11B1 (0.62) | CYP11B1CYP11B2 | |
| SCHEMBL31472005 | 0.69 | CYP11B1 (0.62) | CYP11B1CYP11B2 | |
| SCHEMBL11272431 | 0.69 | LMNA (0.42) | ALDH1A1HSD17B10KDM4EHPGDCYP2C19 | |
| SCHEMBL3684988 | 0.69 | SLC1A3 (0.49) | ALDH1A1HSD17B10KDM4EHPGDCYP3A4 | |
| SCHEMBL27762022 | 0.69 | ADORA2B (0.44) | ALDH1A1CYP11B1CYP11B2TP53CYP1A2 | |
| Ethyl Acetate SCHEMBL27344562 | 0.69 | LMNA (0.44) | ALDH1A1HSD17B10KDM4ETP53CYP1A2 | |
| SCHEMBL9639870 | 0.67 | — | — | |
| SCHEMBL5657511 | 0.67 | CYP11B1 (0.33) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |