Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TCF4 | P15884 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239357 | 0.81 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7271130 | 0.81 | IDO1 (0.62) | MEN1KMT2AALDH1A1MAPK10GFER | |
| SCHEMBL13411338 | 0.81 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL24284171 | 0.80 | MEN1 (0.61) | MEN1KMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL27164642 | 0.71 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7271120 | 0.71 | RAB9A (0.58) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8654120 | 0.70 | MEN1 (0.65) | MEN1KMT2AALDH1A1HPGDATM | |
| SCHEMBL16297206 | 0.70 | KMT2A (0.65) | MEN1KMT2AALDH1A1HPGDATM | |
| SCHEMBL7264088 | 0.70 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL221242 | 0.70 | KMT2A (0.76) | MEN1KMT2AALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |