Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269131 | 0.91 | CACNA1F (0.54) | CACNA1CCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30357940 | 0.91 | CACNA1F (0.54) | CACNA1CCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8928241 | 0.88 | KDM4E (0.53) | CACNA1CCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8928204 | 0.88 | CACNA1C (0.40) | CACNA1CALDH1A1MAPT | |
| SCHEMBL7277695 | 0.88 | CACNA1C (0.48) | CACNA1CCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7275109 | 0.87 | ADORA3 (0.59) | CACNA1CCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8860432 | 0.85 | POLB (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8928281 | 0.84 | POLB (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8928248 | 0.84 | CACNA1C (0.49) | CACNA1CCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10475638 | 0.80 | CACNA1F (0.50) | CACNA1CCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755931-A1 | Dihydropyridine and pyridine derivatives and process for their preparation | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-01-29 | — | — | EP | claimed |
| EP-0755931-A1 | Dihydropyridine and pyridine derivatives and process for their preparation | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-01-29 | — | — | EP | disclosed |