Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294796 | 1.00 | KMT2A (0.42) | KMT2AMEN1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7269535 | 0.80 | AAK1 (0.41) | CYP3A4TSHR | |
| SCHEMBL7275375 | 0.80 | AAK1 (0.41) | CYP3A4TSHR | |
| SCHEMBL7269915 | 0.77 | HPGD (0.44) | KMT2AMEN1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL9555628 | 0.77 | RAB9A (0.38) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1111103 | 0.73 | ADORA2A (0.47) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15130375 | 0.71 | MEN1 (0.42) | KMT2AMEN1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28031146 | 0.71 | TSHR (0.39) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7294807 | 0.71 | REN (0.39) | KMT2AMEN1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7269517 | 0.71 | MEN1 (0.47) | KMT2AMEN1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |