Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.61 |
| ▸ | CTSB | P07858 | 5/20 | 0.61 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.59 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268180 | 0.89 | TACR1 (0.64) | CTSLCTSBCTSKCTSSTACR1 | |
| SCHEMBL7269522 | 0.88 | CTSL (0.62) | CTSLCTSBCTSKCTSSTACR1 | |
| SCHEMBL7267999 | 0.88 | CTSK (0.54) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7268083 | 0.86 | CTSL (0.62) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7268361 | 0.86 | CTSL (0.65) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7268325 | 0.84 | CTSL (0.60) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7269496 | 0.84 | CTSL (0.52) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7285600 | 0.83 | CTSL (0.46) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL10967811 | 0.83 | CAPN1 (0.72) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL9088735 | 0.83 | CAPN1 (0.72) | CTSLCTSBCTSKCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |