Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.52 |
| ▸ | CTSB | P07858 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725792 | 0.95 | CAPN1 (0.56) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7270176 | 0.95 | CAPN1 (0.56) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7268416 | 0.90 | CAPN1 (0.58) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7275313 | 0.85 | CAPN1 (0.57) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL1709147 | 0.85 | CTSL (0.67) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7220623 | 0.85 | CTSL (0.67) | CTSLCTSBCTSKCTSS | |
| SCHEMBL629856 | 0.85 | CTSL (0.67) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7269191 | 0.84 | CTSL (0.61) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL7269500 | 0.84 | CTSL (0.50) | CTSLCTSBCTSKCTSSCAPN1 | |
| SCHEMBL31397623 | 0.83 | CTSL (0.58) | CTSLCTSBCTSKCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |