Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9725813 | 0.93 | CTRB1 (0.45) | EPHX1LAP3ALDH1A1MAPTSRR | |
| SCHEMBL1432589 | 0.83 | ALDH1A1 (0.58) | EPHX1ALDH1A1MAPTSRRALPI | |
| SCHEMBL3901603 | 0.83 | ALDH1A1 (0.58) | EPHX1ALDH1A1MAPTSRRALPI | |
| SCHEMBL20791653 | 0.83 | ALDH1A1 (0.58) | EPHX1ALDH1A1MAPTSRRALPI | |
| Hydrochloric Acid SCHEMBL6895837 | 0.81 | ALDH1A1 (0.60) | EPHX1ALDH1A1MAPTSRRALPI | |
| SCHEMBL7789794 | 0.80 | EPHX1 (0.44) | EPHX1LAP3ALDH1A1MAPTSRR | |
| SCHEMBL7064891 | 0.80 | EPHX1 (0.50) | EPHX1ALDH1A1MAPTSRRALPI | |
| SCHEMBL900942 | 0.79 | ADRA2B (0.54) | EPHX1ALDH1A1MAPTALPIPKM | |
| SCHEMBL4463351 | 0.79 | EPHX1 (0.49) | EPHX1ALDH1A1MAPTALPIPKM | |
| SCHEMBL17992751 | 0.79 | EPHX1 (0.49) | EPHX1ALDH1A1MAPTSRRALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |