Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658389 | 0.83 | ALDH1A1 (0.59) | MAPTALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL2954111 | 0.82 | MAPT (0.62) | MAPTALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL19023499 | 0.78 | MAPT (0.52) | MAPTALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL29901720 | 0.78 | ALDH1A1 (0.63) | MAPTALDH1A1POLBLMNATSHR | |
| SCHEMBL6752 | 0.78 | ALDH1A1 (0.63) | MAPTALDH1A1POLBLMNATSHR | |
| SCHEMBL7270318 | 0.76 | GAA (0.59) | MAPTALDH1A1POLBLMNAUSP2 | |
| SCHEMBL4295708 | 0.74 | ALDH1A1 (0.61) | MAPTALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL352186 | 0.74 | ALDH1A1 (0.68) | MAPTALDH1A1POLBLMNATSHR | |
| SCHEMBL4295310 | 0.74 | ALDH1A1 (0.64) | MAPTALDH1A1SMN1; SMN2LMNACASP3 | |
| SCHEMBL29195060 | 0.73 | MAPT (0.75) | MAPTALDH1A1POLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411751-A1 | Renin inhibitory peptides | Beecham Group p.l.c. (GB) | 1991-02-06 | — | — | EP | disclosed |