Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.61 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131503 | 0.78 | RORC (0.39) | PBRM1RORCABCB1CYP19A1AR | |
| SCHEMBL3683723 | 0.78 | PBRM1 (0.69) | PBRM1TDP1BRD4CREBBPCYP19A1 | |
| SCHEMBL3681000 | 0.78 | PBRM1 (0.69) | PBRM1TDP1BRD4CREBBPCYP19A1 | |
| SCHEMBL8688431 | 0.78 | TDP1 (0.51) | PBRM1ABCB1TDP1CASP3RAB9A | |
| SCHEMBL18013010 | 0.76 | PBRM1 (1.00) | PBRM1ABCB1TDP1BRD4CREBBP | |
| SCHEMBL68075 | 0.76 | PBRM1 (0.67) | PBRM1ABCB1TDP1BRD4CREBBP | |
| SCHEMBL2106757 | 0.76 | PBRM1 (0.67) | PBRM1TDP1BRD4CREBBPCYP19A1 | |
| SCHEMBL1984847 | 0.76 | PBRM1 (0.67) | PBRM1TDP1BRD4CREBBPCYP19A1 | |
| SCHEMBL10076980 | 0.76 | PBRM1 (0.67) | PBRM1ABCB1TDP1BRD4CREBBP | |
| SCHEMBL31015961 | 0.76 | PBRM1 (1.00) | PBRM1ABCB1TDP1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346724-A1 | Chroman derivates | MERCK PATENT GmbH (DE) | 1989-12-20 | — | — | EP | disclosed |