Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.57 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.52 |
| ▸ | HTR3B | O95264 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269469 | 1.00 | CYP2D6 (0.60) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7271039 | 1.00 | CYP2D6 (0.60) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7277894 | 0.99 | CYP2D6 (0.62) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7918881 | 0.97 | CHRNB2 (0.61) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7918883 | 0.97 | CHRNB2 (0.61) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7280163 | 0.89 | CYP2D6 (0.64) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7276029 | 0.88 | RAB9A (0.56) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7270653 | 0.87 | CYP2D6 (0.56) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7299257 | 0.87 | CYP2D6 (0.64) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7270646 | 0.86 | RAB9A (0.54) | CYP2D6ALDH1A1CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |