Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 8/20 | 0.52 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSB | P07858 | 5/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270176 | 1.00 | CAPN1 (0.56) | CAPN1HTRA1CTSLCTSKCTSB | |
| SCHEMBL7269496 | 0.95 | CTSL (0.52) | CAPN1HTRA1CTSLCTSKCTSB | |
| SCHEMBL7268416 | 0.95 | CAPN1 (0.58) | CAPN1HTRA1CTSLCTSKCTSB | |
| SCHEMBL7275313 | 0.90 | CAPN1 (0.57) | CAPN1HTRA1CTSLCTSKCTSB | |
| SCHEMBL16847835 | 0.85 | CTSK (0.69) | CAPN1CTSLCTSKCTSBCTSS | |
| SCHEMBL7270180 | 0.83 | CTSL (0.51) | CAPN1HTRA1CTSLCTSKCTSB | |
| SCHEMBL7269191 | 0.82 | CTSL (0.61) | CAPN1CTSLCTSKCTSBCTSS | |
| SCHEMBL7269500 | 0.81 | CTSL (0.50) | CAPN1HTRA1CTSLCTSKCTSB | |
| SCHEMBL31397623 | 0.81 | CTSL (0.58) | CAPN1CTSLCTSKCTSBCTSS | |
| SCHEMBL1709147 | 0.81 | CTSL (0.67) | CTSLCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |