Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297964 | 0.89 | NPC1 (0.48) | SMN1; SMN2ALDH1A1MAPTRAB9ATSHR | |
| SCHEMBL7270889 | 0.87 | SMN1; SMN2 (0.63) | USP2SMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL7297419 | 0.85 | KMT2A (0.43) | SMN1; SMN2ALDH1A1MAPTRAB9ATSHR | |
| SCHEMBL7296520 | 0.82 | KMT2A (0.45) | SMN1; SMN2ALDH1A1MAPTRAB9ATSHR | |
| SCHEMBL7298043 | 0.76 | NPC1 (0.61) | SMN1; SMN2ALDH1A1MAPTRAB9ATSHR | |
| SCHEMBL7297721 | 0.72 | NPC1 (0.52) | SMN1; SMN2ALDH1A1MAPTRAB9ATSHR | |
| SCHEMBL948677 | 0.69 | GFER (0.71) | POLBALDH1A1RAB9ADRD2DRD3 | |
| SCHEMBL7298589 | 0.67 | KMT2A (0.54) | SMN1; SMN2ALDH1A1MAPTRAB9ATSHR | |
| SCHEMBL7545507 | 0.67 | NR4A2 (0.57) | SMN1; SMN2POLBALDH1A1MAPTTSHR | |
| SCHEMBL7288972 | 0.67 | GABRA1 (0.47) | ALDH1A1MAPTRAB9ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |