Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNG | P07510 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297964 | 0.88 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2HTR4HTR3E | |
| SCHEMBL7297721 | 0.88 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2HTR4HTR3E | |
| SCHEMBL7270889 | 0.87 | SMN1; SMN2 (0.63) | RAB9ASMN1; SMN2HTR4HTR3EHTR3B | |
| SCHEMBL7298589 | 0.82 | KMT2A (0.54) | NPC1RAB9ASMN1; SMN2HTR4HTR3E | |
| SCHEMBL7297419 | 0.78 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2HTR4HTR3E | |
| SCHEMBL7269526 | 0.76 | USP2 (0.52) | RAB9ASMN1; SMN2CYP2D6DRD2DRD3 | |
| SCHEMBL3262552 | 0.74 | NR4A2 (0.69) | SMN1; SMN2HTR4HTR3EHTR3BCYP2D6 | |
| SCHEMBL7615992 | 0.73 | CYP2D6 (0.58) | RAB9ASMN1; SMN2HTR4HTR3EHTR3B | |
| SCHEMBL7278288 | 0.72 | HTR3E (0.56) | NPC1RAB9ASMN1; SMN2HTR4HTR3E | |
| SCHEMBL7271032 | 0.72 | HTR3E (0.56) | NPC1RAB9ASMN1; SMN2HTR4HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124324-A | Psychological disorders, 5-hydroxy tryptamine antagonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |