Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275895 | 0.83 | PGR (0.47) | — | |
| SCHEMBL7268569 | 0.83 | ABCB1 (0.44) | CYP3A4 | |
| SCHEMBL6445021 | 0.82 | PGR (0.46) | — | |
| SCHEMBL6449059 | 0.82 | PGR (0.46) | — | |
| SCHEMBL6447678 | 0.82 | PGR (0.46) | — | |
| SCHEMBL6448984 | 0.82 | ABCB1 (0.43) | CYP3A4 | |
| SCHEMBL9741196 | 0.82 | ABCB1 (0.43) | CYP3A4 | |
| SCHEMBL6454316 | 0.82 | ABCB1 (0.43) | CYP3A4 | |
| SCHEMBL7268965 | 0.81 | CYP3A4 (0.46) | CYP3A4 | |
| SCHEMBL6449476 | 0.80 | LMNA (0.47) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402646-B1 | Retroviral protease inhibiting compounds | ABBOTT LAB (US) | 1998-07-22 | — | — | EP | disclosed |
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |