Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945599 | 0.88 | THRB (0.43) | HPGDSMN1; SMN2THRBMAPTTSHR | |
| SCHEMBL23695683 | 0.83 | ALDH1A1 (0.47) | HPGDSMN1; SMN2THRBMAPTTSHR | |
| SCHEMBL15366668 | 0.83 | TSHR (0.41) | HPGDSMN1; SMN2THRBMAPTTSHR | |
| SCHEMBL4195357 | 0.81 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2THRBMAPTTSHR | |
| SCHEMBL7279182 | 0.81 | ALOX5 (0.40) | ALOX5HPGDSMN1; SMN2MAPTTSHR | |
| SCHEMBL3974470 | 0.79 | ALDH1A1 (0.53) | ALOX5HPGDSMN1; SMN2MAPTTSHR | |
| SCHEMBL13945607 | 0.79 | ALDH1A1 (0.51) | HPGDSMN1; SMN2THRBMAPTTSHR | |
| SCHEMBL16358205 | 0.77 | ALOX5 (0.53) | ALOX5HPGDSMN1; SMN2MAPTTSHR | |
| SCHEMBL25863990 | 0.77 | TSHR (0.40) | ALOX5HPGDSMN1; SMN2THRBTSHR | |
| SCHEMBL4199672 | 0.76 | TSHR (0.53) | HPGDSMN1; SMN2THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |