SCHEMBL726984

SCHEMBL726984

CCCCCCCC=C(O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.60
TSHR P16473 3/20 0.48
TERT O14746 3/20 0.46
PTPN1 P18031 3/20 0.46
PPARG P37231 3/20 0.46
PPARD Q03181 3/20 0.46
PPARA Q07869 3/20 0.46
TOP1 P11387 3/20 0.46
MAPT P10636 2/20 0.46
BLM P54132 2/20 0.46
HSD17B10 Q99714 2/20 0.46
FABP4 P15090 2/20 0.46
GMNN O75496 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
APEX1 P27695 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1493669 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL1574053 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL15351850 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL9189355 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL3677161 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL3085238 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL7103277 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL15350784 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL15350839 1.00 EP300 (0.60) EP300TSHRTERTPTPN1PPARG
SCHEMBL28908165 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530603-B2 Golf ball SRI SPORTS LIMITED (JP) 2013-09-10 US claimed
US-20240376256-A1 ORGANIC BINDER, COMPOSITION FOR PRODUCING INORGANIC MATERIAL MOLDED ARTICLE, GREEN BODY, DEGREASED BODY, INORGANIC MATERIAL MOLDED ARTICLE, AND METHOD OF PRODUCING INORGANIC MATERIAL MOLDED ARTICLE KUREHA CORPORATION (JP) 2024-11-14 US disclosed
CN-114269888-B Fragrance enhancing composition 阿尔门德拉私人有限公司 2024-08-27 CN disclosed
US-11963939-B2 Use of N-acetylcysteine to treat central nervous system disorders Neuronasal, Inc. (US) 2024-04-23 US disclosed
US-20240115533-A1 USE OF N-ACETYLCYSTEINE TO TREAT CNS DISORDERS Burke Neurological Institute 2024-04-11 US disclosed
CN-117529377-A Organic binder, composition for producing inorganic material molded body, green body, degreased body, inorganic material molded body, and method for producing inorganic material molded body 株式会社吴羽 2024-02-06 CN disclosed
US-20230414548-A1 USE OF N-ACETYLCYSTEINE TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS NEURONASAL, LLC 2023-12-28 US disclosed
WO-2023147169-A2 NOVEL LIQUID FORMULATIONS FOR IRON CHELATION LIVIONEX, Inc. (US) 2023-08-03 WO disclosed
US-11707648-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-07-25 US disclosed
US-11660278-B2 Use of N-acetylcysteine to treat central nervous system disorders Neuronasal, Inc. (US) 2023-05-30 US disclosed
WO-2012001687-A2 A NEUROPROTECTIVE NATURAL EXTRACT YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2012-01-05 WO disclosed
US-20100331113-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-12-30 US disclosed
US-20100150895-A1 Nutraceutical agent for attenuating the Neurodegenerative process associated with Parkinson's disease NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-06-17 US disclosed
US-20090111121-A1 METHOD FOR DETECTING A BIOMARKER OF OXIDATIVE STRESS IN A BIOLOGICAL SAMPLE INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) 2009-04-30 US disclosed
CN-101379396-A Method for detecting biomarkers of oxidative stress in biological samples INST CARDIOLOGIE MONTREAL (CA) 2009-03-04 CN disclosed
EP-1934602-A4 METHOD FOR DETECTING A BIOMARKER OF OXIDATIVE STRESS IN A BIOLOGICAL SAMPLE INST CARDIOLOGIE MONTREAL (CA) 2009-01-21 EP disclosed
US-20080292607-A1 Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease MAZZIO ELIZABETH 2008-11-27 US disclosed
EP-1934602-A1 METHOD FOR DETECTING A BIOMARKER OF OXIDATIVE STRESS IN A BIOLOGICAL SAMPLE Institut de Cardiologie de Montréal (CA) 2008-06-25 EP disclosed
US-20070116779-A1 Comprehensive nutraceutical agent for treatment/ prevention of Parkinson's disease MAZZIO ELIZABETH 2007-05-24 US disclosed
WO-2007041868-A1 METHOD FOR DETECTING A BIOMARKER OF OXIDATIVE STRESS IN A BIOLOGICAL SAMPLE INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414548-A1 USE OF N-ACETYLCYSTEINE TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS NLN, ALOX5, AANAT EP300 1531/4885TSHR 3198/4885TERT 2483/4885
US-11963939-B2 Use of N-acetylcysteine to treat central nervous system disorders NLN, ALOX5, AANAT EP300 1531/4885TSHR 3198/4885TERT 2483/4885
US-11660278-B2 Use of N-acetylcysteine to treat central nervous system disorders NLN, ALOX5, AANAT EP300 1531/4885TSHR 3198/4885TERT 2483/4885
US-20240115533-A1 USE OF N-ACETYLCYSTEINE TO TREAT CNS DISORDERS AANAT, ALOX5, PRSS12 EP300 1391/4885TSHR 3618/4885TERT 3103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.