Sugi Predict

Sugi Predict / Compounds / SCHEMBL7270108

SCHEMBL7270108

SCHEMBL7270108

N[C@@H](Cc1ccnc(Cl)c1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.55
▸ SLC7A5 Q01650 5/20 0.53
▸ PTGS1 P23219 2/20 0.53
▸ RECQL P46063 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ USP2 O75604 1/20 0.53
▸ EGFR P00533 1/20 0.53
▸ LCK P06239 1/20 0.53
▸ FYN P06241 1/20 0.53
▸ ADORA3 P0DMS8 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ HTR2A P28223 1/20 0.53
▸ PTGS2 P35354 1/20 0.53
▸ HIF1A Q16665 1/20 0.53
▸ TDP1 Q9NUW8 1/20 0.53
▸ PKM P14618 2/20 0.51
▸ LOX P28300 1/20 0.51
▸ LOXL3 P58215 1/20 0.51
▸ LOXL2 Q9Y4K0 1/20 0.51
▸ ALPI P09923 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556838 1.00 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL5285356 1.00 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL29604446 0.82 GABRP (0.60) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL22775321 0.82 GABRP (0.60) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL14780595 0.82 GABRP (0.60) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL25354508 0.82 GABRP (0.60) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL15562033 0.81 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL31073989 0.81 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL22775485 0.81 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1RECQLKDM4E
SCHEMBL15562032 0.81 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1RECQLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 — — US disclosed
US-11891422-B2 NEMO coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2024-02-06 — — US disclosed
EP-4013440-A1 THERAPEUTIC PEPTIDES Cohbar Inc. (US) 2022-06-22 — — EP disclosed
CN-114269367-A Therapeutic peptides 科巴公司 2022-04-01 — — CN disclosed
CN-113518784-A Therapeutic peptides 科巴公司 2021-10-19 — — CN disclosed
US-20210277059-A1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2021-09-09 — — US disclosed
US-11111271-B2 Therapeutic peptides COHBAR, INC. (US) 2021-09-07 — — US disclosed
WO-2021030794-A1 THERAPEUTIC PEPTIDES COHBAR, INC. (US) 2021-02-18 — — WO disclosed
WO-2021030792-A1 THERAPEUTIC PEPTIDES COHBAR, INC. (US) 2021-02-18 — — WO disclosed
WO-2021030687-A1 THERAPEUTIC PEPTIDES COHBAR, INC. (US) 2021-02-18 — — WO disclosed
WO-2021030752-A1 THERAPEUTIC PEPTIDES COHBAR, INC. (US) 2021-02-18 — — WO disclosed
WO-2021030469-A1 THERAPEUTIC MITOCHONDRIAL PEPTIDES COHBAR, INC. (US) 2021-02-18 — — WO disclosed
US-10851133-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2020-12-01 — — US disclosed
US-20200190155-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2020-06-18 — — US disclosed
US-20200181197-A1 THERAPEUTIC PEPTIDES COHBAR, INC. 2020-06-11 — — US disclosed
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS NEW YORK UNIVERSITY 2018-06-14 — — US disclosed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 — — US disclosed
EP-0073143-B1 NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES Ryan, James Walter (US) 1985-11-21 — — EP disclosed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 — — EP disclosed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10851133-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, CRYZ HSD17B10 3638/4885SLC7A5 1374/4885PTGS1 4479/4885
US-20210277059-A1 STABILIZED MINIMAL COILED-COIL MIMETICS COIL, CALCOCO2, CRYZ HSD17B10 3638/4885SLC7A5 1374/4885PTGS1 4479/4885
US-11891422-B2 NEMO coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH HSD17B10 1813/4885SLC7A5 3871/4885PTGS1 962/4885
US-20200190155-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH HSD17B10 1813/4885SLC7A5 3871/4885PTGS1 962/4885
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS COIL, CALCOCO2, CRYZ HSD17B10 3638/4885SLC7A5 1374/4885PTGS1 4479/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH HSD17B10 1858/4885SLC7A5 4057/4885PTGS1 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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