Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485099 | 0.90 | NOTUM (0.38) | ALDH1A1SMN1; SMN2SLC5A2KDM4EFFAR4 | |
| SCHEMBL9485028 | 0.85 | FFAR4 (0.36) | DRD2ALDH1A1FFAR4HTT | |
| SCHEMBL9485223 | 0.83 | DRD2 (0.36) | DRD2ALDH1A1KDM4EFFAR4 | |
| SCHEMBL9485840 | 0.83 | FFAR4 (0.37) | ALDH1A1FFAR4NOTUM | |
| SCHEMBL9485751 | 0.81 | HTR3A (0.53) | KCNH2 | |
| SCHEMBL7270656 | 0.79 | DRD2 (0.52) | DRD2ADRA1DSIGMAR1ALDH1A1ALDH2 | |
| SCHEMBL7276148 | 0.79 | CYP3A4 (0.37) | DRD2ALDH1A1FFAR4NOTUMTP53 | |
| SCHEMBL7288574 | 0.77 | ALDH1A1 (0.44) | DRD2ADRA1DALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7280877 | 0.74 | ALDH1A1 (0.40) | DRD2ADRA1DALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7276032 | 0.71 | DRD2 (0.35) | DRD2MAPTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |