Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18033973 | 0.89 | HTT (0.44) | ALDH1A1HTTTSHRMAPTKMT2A | |
| SCHEMBL321080 | 0.80 | TPMT (0.48) | ALDH1A1HTTTSHRKMT2ALMNA | |
| SCHEMBL14339400 | 0.80 | KMT2A (0.42) | ALDH1A1HTTTSHRMAPTKMT2A | |
| SCHEMBL5783909 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2AGPR35HPGD | |
| SCHEMBL333570 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPTKMT2ALMNA | |
| SCHEMBL7265798 | 0.78 | POLB (0.48) | ALDH1A1HTTTSHRMAPTKMT2A | |
| SCHEMBL31619409 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL246394 | 0.77 | TAS1R3 (0.41) | ALDH1A1HTTTSHRMAPTKMT2A | |
| SCHEMBL104060 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HTTTSHRMAPTKMT2A | |
| SCHEMBL15571512 | 0.76 | POLB (0.39) | ALDH1A1MAPTKMT2AGPR35HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201152-B1 | HEATING MIXTURE OF METHYL-3,5-DICHLORO-4-METHYLBENZOATE AND ALPHA,ALPHA,ALPHA-TRICHLOROMETHYLBENZENE IN PRESENCE OF AMMONIUM MOLYBDATE CATALYST | OCCIDENTAL CHEMICAL CORPORATION | 2001-03-13 | — | — | US | claimed |
| EP-0816328-A2 | Process for the manufacture of acetonylbenzamides | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | claimed |
| US-5113016-A | Manufacture of phthaloyl chlorides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-12 | — | — | US | claimed |
| US-8957228-B2 | Macrolide compound having anticancer effect | TOHOKU UNIVERSITY (JP) | 2015-02-17 | — | — | US | disclosed |
| US-20130281714-A1 | MACROLIDE COMPOUND HAVING ANTICANCER EFFECT | TOHOKU UNIVERSITY (JP) | 2013-10-24 | — | — | US | disclosed |
| US-6429334-B1 | CATALYTIC REACTION OF ORGANIC ACID OR ANHYDRIDE AND PHOSGENE IN GROUP IV METAL HALIDE PRESENCE; CHLORINATION, BROMINATION, HALOGENATION, CATALYSIS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-08-06 | — | — | US | disclosed |
| US-6201152-B1 | HEATING MIXTURE OF METHYL-3,5-DICHLORO-4-METHYLBENZOATE AND ALPHA,ALPHA,ALPHA-TRICHLOROMETHYLBENZENE IN PRESENCE OF AMMONIUM MOLYBDATE CATALYST | OCCIDENTAL CHEMICAL CORPORATION | 2001-03-13 | — | — | US | disclosed |
| US-6201152-B1 | HEATING MIXTURE OF METHYL-3,5-DICHLORO-4-METHYLBENZOATE AND ALPHA,ALPHA,ALPHA-TRICHLOROMETHYLBENZENE IN PRESENCE OF AMMONIUM MOLYBDATE CATALYST | OCCIDENTAL CHEMICAL CORPORATION | 2001-03-13 | — | — | US | disclosed |
| US-6201152-B1 | HEATING MIXTURE OF METHYL-3,5-DICHLORO-4-METHYLBENZOATE AND ALPHA,ALPHA,ALPHA-TRICHLOROMETHYLBENZENE IN PRESENCE OF AMMONIUM MOLYBDATE CATALYST | OCCIDENTAL CHEMICAL CORPORATION | 2001-03-13 | — | — | US | disclosed |
| US-5969200-A | CHLORINATING PARA-TOLUOYL CHLORIDE IN PRESENCE OF CHLORINE GAS AND ALUMINUM CHLORIDE OR ANTIMONY CHLORIDE CATALYST, DISTILLING MIXTURE PRODUCED TO RECOVER 3,5-DICHLORO-4-METHYLBENZOYL CHLORIDE | ROHM AND HAAS COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5945565-A | SYNTHESIS OF 4-AMINO-3-CHLORO-5-(METHOXYIMINOMETHYL)BENZOYL CHLORIDE STARTING WITH THE CONVERSION OF 5-METHYL-4-NITRO-BENZOIC ACID TO 4-NITRO-5-(METHOXYIMINOMETHYL)-BENZOIC ACID, METHYL ESTER | ROHM AND HAAS COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| US-5874466-A | REACTING AMINE AND ACYL CHLORIDE, HYDROGENOLYSIS | ROHM AND HAAS COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0816328-A2 | Process for the manufacture of acetonylbenzamides | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5113016-A | Manufacture of phthaloyl chlorides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0151529-B1 | 5-(AMINO OR SUBSTITUTED AMINO)-1,2,3-TRIAZOLES | MERCK & CO. INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4590201-A | ANTICOCCIDIAL AGENT FOR ANIMALS PARTICULARLY FOR POULTRY | MERCK & CO., INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151529-A2 | 5-(Amino or substituted amino)-1,2,3-triazoles | MERCK & CO. INC. (US) | 1985-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281714-A1 | MACROLIDE COMPOUND HAVING ANTICANCER EFFECT | HDAC6, RPL21, MKI67 | ALDH1A1 3785/4885HTT 2250/4885TSHR 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.