Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278264 | 0.91 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7278244 | 0.81 | CYP3A4 (0.54) | MEN1KMT2AALDH1A1POLBMAPK1 | |
| SCHEMBL7270859 | 0.78 | POLB (0.41) | MAPTALDH1A1TDP1POLBMAPK1 | |
| SCHEMBL7270181 | 0.74 | POLB (0.46) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7280026 | 0.74 | NPSR1 (0.62) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL26931958 | 0.73 | NAMPT (0.47) | GAAL3MBTL1 | |
| SCHEMBL26932141 | 0.73 | NAMPT (0.47) | POLBGAAL3MBTL1LMNA | |
| SCHEMBL7270138 | 0.72 | KMO (0.56) | MAPTALDH1A1POLBMAPK1GAA | |
| SCHEMBL9850703 | 0.71 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL15875389 | 0.70 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411751-A1 | Renin inhibitory peptides | Beecham Group p.l.c. (GB) | 1991-02-06 | — | — | EP | disclosed |