Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344999 | 0.80 | HPGD (0.46) | HPGDADORA1ABL1PDGFRBPDGFRA | |
| SCHEMBL7272115 | 0.80 | HPGD (0.43) | HPGDADORA1CYP19A1CYP2D6CYP2C9 | |
| SCHEMBL7264558 | 0.78 | CYP11B2 (0.64) | PIK3CDPIK3CAPI4KAPI4KBCYP19A1 | |
| SCHEMBL15341950 | 0.77 | HPGD (0.41) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL2405218 | 0.77 | CYP19A1 (0.54) | PIK3CACYP19A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31140248 | 0.77 | CYP19A1 (0.54) | PIK3CACYP19A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7270915 | 0.74 | ADORA1 (0.42) | HPGDADORA1CYP19A1PDGFRBPDGFRA | |
| SCHEMBL7272193 | 0.74 | PDGFRB (0.41) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL12695592 | 0.72 | BACE1 (0.57) | HPGDADORA1CYP19A1PDGFRBPDGFRA | |
| SCHEMBL16573997 | 0.72 | PDGFRB (0.46) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710507-A | Quinolone inotropic agents | PFIZER INC. (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0148623-A2 | Quinolone inotropic agents | Pfizer Limited (GB) | 1985-07-17 | — | — | EP | disclosed |