Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271233 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL3070804 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL7658914 | 0.80 | POLB (0.57) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL28643500 | 0.79 | THRB (0.51) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL22920686 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL22691765 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL10923640 | 0.76 | HCAR2 (0.59) | SMN1; SMN2ALDH1A1L3MBTL1TSHRMAPT | |
| SCHEMBL3295702 | 0.76 | TSHR (0.39) | ALDH1A1TSHRMAPTCYP3A4CYP2C19 | |
| Acrylic Acid SCHEMBL31590930 | 0.75 | THRB (0.51) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR | |
| SCHEMBL28860065 | 0.75 | NPC1 (0.54) | SMN1; SMN2POLBALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207514-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4824837-A | VASODILATORS | SUNTORY LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0207514-A2 | 1,4-Dihydropyridine derivatives, process for preparing them, pharmaceutical composition and use | SUNTORY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |