Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643500 | 0.84 | THRB (0.51) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL22691765 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| Acrylic Acid SCHEMBL31590930 | 0.80 | THRB (0.51) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL28860065 | 0.80 | NPC1 (0.54) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7271233 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7271237 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8684761 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7658914 | 0.78 | POLB (0.57) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3070804 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20809605 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | SOOCHOW UNIVERSITY (CN) | 2023-02-23 | — | — | US | disclosed |
| US-11072589-B2 | 1,2,4-triazole and preparation method therefor | SOOCHOW UNIVERSITY | 2021-07-27 | — | — | US | disclosed |
| US-20210024472-A1 | 1,2,4-TRIAZOLE AND PREPARATION METHOD THEREFOR | SOOCHOW UNIVERSITY (CN) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072589-B2 | 1,2,4-triazole and preparation method therefor | CYP4F11, CYP3A4, WEE1 | SMN1; SMN2 4133/4885POLB 2217/4885ALDH1A1 949/4885 |
| US-20230054928-A1 | METHOD FOR PREPARING CARBONYL SULFONE | TST, CBS, STS | SMN1; SMN2 2931/4885POLB 1295/4885ALDH1A1 297/4885 |
| US-20210024472-A1 | 1,2,4-TRIAZOLE AND PREPARATION METHOD THEREFOR | CYP4F11, CYP3A4, WEE1 | SMN1; SMN2 4133/4885POLB 2217/4885ALDH1A1 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.