Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | TRHR | P34981 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272143 | 0.92 | OPRM1 (0.54) | OPRM1TRHR | |
| SCHEMBL7272470 | 0.86 | TRHR (0.42) | TRHR | |
| SCHEMBL7273516 | 0.85 | TRHR (0.42) | TRHR | |
| SCHEMBL7273636 | 0.84 | ACE (0.42) | ACETRHR | |
| SCHEMBL7272196 | 0.84 | CAPN1 (0.43) | TRHR | |
| SCHEMBL7273642 | 0.83 | TRHR (0.41) | TRHR | |
| SCHEMBL7273256 | 0.83 | TRHR (0.54) | OPRM1ACETRHR | |
| SCHEMBL7333526 | 0.83 | TRHR (0.51) | TRHR | |
| SCHEMBL7281074 | 0.82 | ACE (0.44) | ACETRHR | |
| SCHEMBL7271234 | 0.82 | OPRM1 (0.54) | OPRM1ACETRHRACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | claimed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | claimed |
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |