Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7271661 | 0.99 | NPC1 (0.46) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| SCHEMBL7281131 | 0.86 | NPBWR1 (0.52) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL7279969 | 0.84 | NPBWR1 (0.51) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| SCHEMBL10984109 | 0.83 | JMJD6 (0.45) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| SCHEMBL10417452 | 0.83 | JMJD6 (0.39) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| SCHEMBL7270925 | 0.81 | PDE5A (0.56) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| SCHEMBL10415589 | 0.81 | PDE5A (0.43) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| SCHEMBL7280960 | 0.78 | PDE5A (0.45) | NPC1RAB9AJMJD6ACHEALDH1A1 | |
| SCHEMBL7270973 | 0.78 | HPGD (0.48) | NPC1RAB9AJMJD6ALDH1A1MAPT | |
| SCHEMBL10416982 | 0.76 | ALDH1A1 (0.39) | NPC1RAB9AJMJD6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904785-A | INOTROPIC AGENTS FOR CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4758574-A | 2-phenylimidazio (4,5-c) pyridines | ELI LILLY AND COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0093593-A2 | Pyridine compounds | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |