SCHEMBL727202

SCHEMBL727202

CCCCCCCCCC(CC)OCC

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.42
LMNA P02545 1/20 0.39
DNM1 Q05193 3/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
SMPD1 P17405 3/20 0.36
GPR84 Q9NQS5 3/20 0.35
FDPS P14324 3/20 0.35
SPHK1 Q9NYA1 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11453471 1.00 OPRM1 (0.42) OPRM1LMNADNM1TSHRTHRB
SCHEMBL28289881 0.98 OPRM1 (0.44) OPRM1LMNADNM1TSHRTHRB
SCHEMBL28096431 0.93 THRB (0.38) OPRM1LMNATHRB
SCHEMBL4263417 0.90 OPRM1 (0.46) OPRM1LMNADNM1TSHRTHRB
SCHEMBL6554404 0.90 OPRM1 (0.46) OPRM1LMNADNM1TSHRTHRB
SCHEMBL23270390 0.90 OPRM1 (0.46) OPRM1LMNADNM1TSHRTHRB
SCHEMBL28744275 0.90 OPRM1 (0.46) OPRM1LMNADNM1TSHRTHRB
SCHEMBL19060744 0.90 ALDH1A1 (0.37) OPRM1LMNADNM1TSHRTHRB
SCHEMBL4557947 0.90 OPRM1 (0.46) OPRM1LMNADNM1TSHRTHRB
SCHEMBL20225052 0.90 OPRM1 (0.46) OPRM1LMNADNM1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575807-A1 FORMULATION BASED ON SULPIRIDE AND A SYNERGISTIC HOMEOPATHIC COMPOSITION FOR TREATMENT OF DEPRESSIVE SYNDROME Novak, Maja (HR) 2013-04-10 EP claimed
WO-2011148203-A1 FORMULATION BASED ON SULPIRIDE AND A SYNERGISTIC HOMEOPATHIC COMPOSITION FOR TREATMENT OF DEPRESSIVE SYNDROME NOVAK MAJA (HR) 2011-12-01 WO claimed
CN-101023123-A Film-like polymer structure and method for producing same OXYGENIX CO LTD (JP) 2007-08-22 CN disclosed
EP-0955046-B1 Amino acid derivatives as anti-inflammatory agents AJINOMOTO KK (JP) 2005-06-22 EP disclosed
EP-1064373-A2 IDENTIFICATION OF FACTORS WHICH MEDIATE THE INTERACTION OF HETEROTRIMERIC G PROTEINS AND MONOMERIC G PROTEINS ONYX PHARMACEUTICALS, INC. (US) 2001-01-03 EP disclosed
WO-1999047557-A2 IDENTIFICATION OF FACTORS WHICH MEDIATE THE INTERACTION OF HETEROTRIMERIC G PROTEINS AND MONOMERIC G PROTEINS ONYX PHARMACEUTICALS, INC. (US) 1999-09-23 WO disclosed
EP-0083619-A1 A STABLE AQUEOUS, THERAPEUTIC INSULIN PREPARATION AND A PROCESS FOR PREPARING IT NORDISK INSULINLABORATORIUM (DK) 1983-07-20 EP disclosed
WO-1983000288-A1 A STABLE AQUEOUS, THERAPEUTIC INSULIN PREPARATION AND A PROCESS FOR PREPARING IT BALSCHMIDT, PER 1983-02-03 WO disclosed