SCHEMBL7272247

SCHEMBL7272247

Cc1ccc2c(c1)Cc1c-2cccc1[Zr](Cl)(Cl)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ACHE P22303 1/20 0.31
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7269971 0.91 MEN1 (0.32) GAARAB9AACHE
SCHEMBL673541 0.88 PNMT (0.35) RAB9A
SCHEMBL7271195 0.84 ACHE (0.33) ACHE
SCHEMBL7598097 0.76 PNMT (0.35) RAB9A
SCHEMBL29844004 0.76 PNMT (0.35) RAB9A
Hydrochloric Acid SCHEMBL7272238 0.73 KDM4E (0.33) KDM4EALDH1A1POLBGAAMAPT
SCHEMBL2479390 0.72 CA1 (0.37)
SCHEMBL7272264 0.72 PNMT (0.35) RAB9A
SCHEMBL7265200 0.71 PNMT (0.35) RAB9A
SCHEMBL797548 0.70 PNMT (0.33) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270615-A1 ETHYLENE-BASE COPOLYMERS, PROCESS FOR PRODUCING THE SAME AND LUBRICATING OIL COMPOSITIONS CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-02 EP disclosed