Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844004 | 1.00 | PNMT (0.35) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL673541 | 0.85 | PNMT (0.35) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL797548 | 0.80 | PNMT (0.33) | PNMTNPC1RAB9A | |
| SCHEMBL7939383 | 0.79 | — | — | |
| SCHEMBL7272247 | 0.76 | KDM4E (0.33) | RAB9A | |
| SCHEMBL7269971 | 0.76 | MEN1 (0.32) | PNMTNPC1RAB9A | |
| SCHEMBL8163474 | 0.74 | PNMT (0.33) | PNMTNPC1RAB9A | |
| SCHEMBL5823610 | 0.74 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7271195 | 0.72 | ACHE (0.33) | — | |
| SCHEMBL30536713 | 0.72 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| US-6255531-B1 | POLYMERIZATION CATALYSTS | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |