Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.67 |
| ▸ | CACNA1F | O60840 | 7/20 | 0.67 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.67 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712629 | 0.91 | MAPT (0.77) | MAPTMEN1KMT2ATDP1CACNA1C | |
| SCHEMBL7266643 | 0.90 | CACNA1F (0.80) | MAPTMEN1KMT2ACACNA1CCACNA1F | |
| SCHEMBL7271700 | 0.89 | MEN1 (0.74) | MAPTMEN1KMT2ATDP1CACNA1C | |
| SCHEMBL11739916 | 0.88 | MAPT (0.80) | MAPTMEN1KMT2ATDP1CACNA1C | |
| SCHEMBL7274713 | 0.87 | CYP1A2 (0.67) | MAPTMEN1KMT2ATDP1CACNA1C | |
| SCHEMBL10759264 | 0.86 | MEN1 (0.71) | MAPTMEN1KMT2ATDP1CACNA1C | |
| SCHEMBL7271271 | 0.85 | CYP1A2 (0.91) | MAPTMEN1KMT2ATDP1CACNA1C | |
| SCHEMBL7274412 | 0.85 | HIF1A (0.76) | MAPTMEN1KMT2ATDP1CACNA1C | |
| SCHEMBL10901192 | 0.84 | CACNA1F (0.89) | MAPTMEN1KMT2ACACNA1CCACNA1F | |
| SCHEMBL11199449 | 0.84 | CACNA1F (0.80) | MAPTMEN1KMT2ACACNA1CCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207514-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4824837-A | VASODILATORS | SUNTORY LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0207514-A2 | 1,4-Dihydropyridine derivatives, process for preparing them, pharmaceutical composition and use | SUNTORY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |