Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25917394 | 0.84 | RXRA (0.39) | RXRARXRBRXRGALDH1A1CYP4F2 | |
| SCHEMBL24179486 | 0.84 | CYP4F2 (0.39) | RXRARXRBRXRGALDH1A1CYP4F2 | |
| SCHEMBL1141392 | 0.83 | ATR (0.47) | RXRARXRBRXRGALDH1A1CYP4F2 | |
| SCHEMBL30723809 | 0.81 | RXRA (0.46) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL10770777 | 0.80 | ALDH1A1 (0.39) | ALDH1A1GLACYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL10770970 | 0.80 | ALDH1A1 (0.39) | ALDH1A1GLACYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL10770782 | 0.80 | ALDH1A1 (0.39) | ALDH1A1GLACYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL10775607 | 0.80 | ALDH1A1 (0.39) | ALDH1A1GLACYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL10775612 | 0.80 | ALDH1A1 (0.39) | ALDH1A1GLACYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL4572292 | 0.78 | CYP4F2 (0.46) | RXRARXRBRXRGALDH1A1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479962-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-10-30 | — | — | US | disclosed |
| EP-0071950-A1 | Heteroarylpropanol amines, process for preparing them and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1983-02-16 | — | — | EP | disclosed |