SCHEMBL25917394

SCHEMBL25917394

BrCCOc1cccc2c1cnn2C1CCCCO1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 0.39
▸ RXRB P28702 1/20 0.39
▸ RXRG P48443 1/20 0.39
▸ CYP4F2 P78329 5/20 0.38
▸ CYP4A11 Q02928 5/20 0.38
▸ MAPK8 P45983 5/20 0.37
▸ MAPK9 P45984 5/20 0.37
▸ MAPK10 P53779 4/20 0.37
▸ ALDH1A1 P00352 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ BCHE P06276 2/20 0.34
▸ HTR6 P50406 2/20 0.34
▸ ATR Q13535 2/20 0.33
▸ SCN9A Q15858 1/20 0.33
▸ KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24179486 0.89 CYP4F2 (0.39) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL30723809 0.85 RXRA (0.46) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL7272765 0.84 RXRA (0.39) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL1141392 0.83 ATR (0.47) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL30724136 0.81 ALOX5AP (0.39) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL25917464 0.80 RXRA (0.40) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL1760288 0.80 RXRA (0.43) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL25917465 0.79 RXRA (0.37) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL156398 0.78 RXRA (0.42) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL29416187 0.78 RXRA (0.42) RXRARXRBRXRGCYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242507-A1 INDAZOLE-FUSED CYCLIC COMPOUND Zhejiang Yangli Pharmaceutical Technology Co., Ltd. (CN) 2023-08-03 — — US disclosed
US-20230242507-A1 INDAZOLE-FUSED CYCLIC COMPOUND Zhejiang Yangli Pharmaceutical Technology Co., Ltd. (CN) 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242507-A1 INDAZOLE-FUSED CYCLIC COMPOUND SLC5A11, CYP11B2, CYP4F11 RXRA 3699/4885RXRB 3804/4885RXRG 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback