Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7281378 | 0.99 | DRD2 (0.59) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| SCHEMBL6535583 | 0.92 | GRIN2B (0.69) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL20985478 | 0.91 | GRIN2B (0.67) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| SCHEMBL11075369 | 0.90 | DRD2 (0.70) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| SCHEMBL7270986 | 0.88 | ADRA1A (0.65) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| SCHEMBL7270896 | 0.88 | ADRA1A (0.65) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| Bromide SCHEMBL9792055 | 0.87 | ADRA1A (0.64) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| Bromide SCHEMBL7271982 | 0.87 | ADRA1A (0.64) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| SCHEMBL7281491 | 0.87 | ADRA1A (0.63) | DRD2DRD4DRD3GRIN2BSIGMAR1 | |
| Bromide SCHEMBL7272021 | 0.86 | ADRA1A (0.62) | DRD2DRD4DRD3GRIN2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072061-A1 | Amine derivatives, processes for their production and pharmaceutical compositions containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | claimed |