SCHEMBL6535583

SCHEMBL6535583

Oc1cccc2c1CCC(NCCCCCc1ccccc1)C2

nearest known ligand 0.74

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 11/20 0.69
DRD2 P14416 1/20 0.64
DRD4 P21917 1/20 0.64
DRD3 P35462 1/20 0.64
SIGMAR1 Q99720 4/20 0.63
GRIN1 Q05586 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20985478 0.99 GRIN2B (0.67) GRIN2BDRD2DRD4DRD3SIGMAR1
SCHEMBL7272848 0.92 DRD2 (0.60) GRIN2BDRD2DRD4DRD3SIGMAR1
Bromide SCHEMBL7281378 0.91 DRD2 (0.59) GRIN2BDRD2DRD4DRD3SIGMAR1
SCHEMBL11075369 0.90 DRD2 (0.70) GRIN2BDRD2DRD4DRD3SIGMAR1
SCHEMBL7329677 0.86 GRIN2B (0.69) GRIN2BDRD2DRD3SIGMAR1GRIN1
Hydrochloric Acid SCHEMBL7326858 0.85 GRIN2B (0.67) GRIN2BDRD2DRD3SIGMAR1GRIN1
Hydrochloric Acid SCHEMBL7334760 0.85 GRIN2B (0.67) GRIN2BDRD2DRD3SIGMAR1GRIN1
Hydrochloric Acid SCHEMBL7329362 0.85 GRIN2B (0.67) GRIN2BDRD2DRD3SIGMAR1GRIN1
Hydrochloric Acid SCHEMBL7337819 0.85 GRIN2B (0.67) GRIN2BDRD2DRD3SIGMAR1GRIN1
Hydrochloric Acid SCHEMBL7333173 0.85 GRIN2B (0.67) GRIN2BDRD2DRD3SIGMAR1GRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717276-A2 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER University of Canberra (AU) 2026-04-01 EP claimed
EP-3442516-B1 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER UNIV CANBERRA (AU) 2025-11-12 EP claimed
US-11890266-B2 Ophthalmic compositions including levodopa, an antioxidant and an aqueous carrier UNIVERSITY OF CANBERRA (AU) 2024-02-06 US claimed
US-20220047529-A1 METHODS OF INHIBITION UNIVERSITY OF CANBERRA (AU) 2022-02-17 US claimed
US-20210077443-A1 OPHTHALMIC COMPOSITIONS INCLUDING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER UNIVERSITY OF CANBERRA (AU) 2021-03-18 US claimed
US-10874629-B2 Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier UNIVERSITY OF CANBERRA (AU) 2020-12-29 US claimed
US-20190151270-A1 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER UNIVERSITY OF CANBERRA (AU) 2019-05-23 US claimed
EP-4717276-A2 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER University of Canberra (AU) 2026-04-01 EP disclosed
EP-3442516-B1 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER UNIV CANBERRA (AU) 2025-11-12 EP disclosed
US-11890266-B2 Ophthalmic compositions including levodopa, an antioxidant and an aqueous carrier UNIVERSITY OF CANBERRA (AU) 2024-02-06 US disclosed
US-20220047529-A1 METHODS OF INHIBITION UNIVERSITY OF CANBERRA (AU) 2022-02-17 US disclosed
US-20210077443-A1 OPHTHALMIC COMPOSITIONS INCLUDING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER UNIVERSITY OF CANBERRA (AU) 2021-03-18 US disclosed
US-10874629-B2 Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier UNIVERSITY OF CANBERRA (AU) 2020-12-29 US disclosed
US-20190151270-A1 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER UNIVERSITY OF CANBERRA (AU) 2019-05-23 US disclosed
EP-0765477-A4 RESINS FOR SOLID STATE SYNTHESIS SMITHKLINE BEECHAM CORP (US) 2004-11-17 EP disclosed
EP-0765477-A1 RESINS FOR SOLID STATE SYNTHESIS SMITHKLINE BEECHAM CORPORATION (US) 1997-04-02 EP disclosed
WO-1995034813-A1 RESINS FOR SOLID STATE SYNTHESIS SMITHKLINE BEECHAM CORPORATION (US) 1995-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220047529-A1 METHODS OF INHIBITION SLC6A3, DBH, SNCA GRIN2B 659/4885DRD2 5/4885DRD4 8/4885
US-11890266-B2 Ophthalmic compositions including levodopa, an antioxidant and an aqueous carrier TTPA, TST, TXN2 GRIN2B 2994/4885DRD2 2171/4885DRD4 2073/4885
US-10874629-B2 Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier COMT, LRRK2, PARK7 GRIN2B 1014/4885DRD2 225/4885DRD4 187/4885
US-20190151270-A1 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER COMT, LRRK2, PARK7 GRIN2B 1014/4885DRD2 225/4885DRD4 187/4885
US-20210077443-A1 OPHTHALMIC COMPOSITIONS INCLUDING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER TTPA, TST, TXN2 GRIN2B 2994/4885DRD2 2171/4885DRD4 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.