SCHEMBL7272874

SCHEMBL7272874

O=C1CCNC2=CC=CCN12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6632296 0.66 CRBN (0.30) CRBN
SCHEMBL161377 0.64
SCHEMBL15574709 0.63
SCHEMBL1752650 0.62 CHRNB2 (0.33)
SCHEMBL28643558 0.62
SCHEMBL21617872 0.59 CRBN (0.37) CRBN
SCHEMBL3322087 0.59
SCHEMBL195402 0.57
SCHEMBL8793212 0.57 CA12 (0.33)
SCHEMBL9614870 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116925071-A Preparation method of paliperidone palmitate photodegradation impurity 丽珠医药集团股份有限公司 2023-10-24 CN disclosed
WO-2012151567-A1 PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2012-11-08 WO disclosed
US-4568677-A CONTROLLED COOLING PFIZER INC. (US) 1986-02-04 US disclosed
EP-0132375-A2 Dihydropyridine anti-ischaemic and antihypertensive agents Pfizer Limited (GB) 1985-01-30 EP disclosed