Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709772 | 0.67 | — | — | |
| SCHEMBL19004321 | 0.65 | — | — | |
| SCHEMBL7215990 | 0.60 | APAF1 (0.32) | — | |
| SCHEMBL7272874 | 0.59 | CRBN (0.31) | CRBN | |
| SCHEMBL6030491 | 0.58 | CRBN (0.43) | CRBNDDB1 | |
| Succinimide SCHEMBL28635055 | 0.57 | CRBN (0.79) | CRBNDDB1 | |
| Succinimide SCHEMBL27849600 | 0.57 | CRBN (0.79) | CRBNDDB1 | |
| SCHEMBL15063081 | 0.56 | — | — | |
| SCHEMBL33371399 | 0.56 | CRBN (0.33) | CRBNDDB1 | |
| SCHEMBL8719021 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490431-A | Novel small molecule inhibitors of TEAD transcription factors | 总医院公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-113811300-B | Novel small molecule inhibitors of TEAD transcription factors | 总医院公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2020012357-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2020-01-16 | — | — | WO | disclosed |