Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4169139 | 0.81 | ACP3 (0.40) | TSHR | |
| SCHEMBL2542920 | 0.79 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL11307453 | 0.75 | SLC6A3 (0.50) | — | |
| SCHEMBL5070145 | 0.73 | ALDH1A1 (0.38) | ERN1TSHR | |
| Hexane SCHEMBL11469486 | 0.72 | ALDH1A1 (0.44) | TSHR | |
| SCHEMBL7282298 | 0.72 | ALDH1A1 (0.37) | ERN1TSHR | |
| SCHEMBL7282307 | 0.72 | ALDH1A1 (0.37) | ERN1TSHR | |
| SCHEMBL4168433 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL17431765 | 0.70 | TSHR (0.42) | ERN1TSHR | |
| SCHEMBL9489967 | 0.70 | TSHR (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679645-A1 | Pharmacologically active CNS pyridmidin compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-02 | — | — | EP | disclosed |
| EP-0459819-A2 | Pharmacologically active CNS compound | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |