Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272895 | 0.86 | CPT2 (0.47) | ALDH1A1PREPPKMHTTSMN1; SMN2 | |
| SCHEMBL7313161 | 0.84 | ALDH1A1 (0.44) | ALDH1A1PREPCHRM2CHRM3CHRM1 | |
| SCHEMBL7275012 | 0.83 | CPT2 (0.49) | ALDH1A1PREPPKMHTTSMN1; SMN2 | |
| SCHEMBL7267053 | 0.78 | ALDH1A1 (0.45) | ALDH1A1PREPCHRM2CHRM3CHRM1 | |
| SCHEMBL7325895 | 0.77 | PREP (0.44) | PREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7325890 | 0.77 | PREP (0.44) | PREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7274881 | 0.77 | CPT2 (0.47) | ALDH1A1PREPPKMHTTSMN1; SMN2 | |
| SCHEMBL8633510 | 0.76 | F2 (0.53) | ALDH1A1PKM | |
| SCHEMBL7265280 | 0.76 | F2 (0.53) | ALDH1A1PKM | |
| SCHEMBL7324911 | 0.75 | PREP (0.44) | PREPNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | claimed |
| EP-0268190-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0268190-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | claimed |
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| US-5254550-A | Enzyme inhibitor | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| US-4956380-A | COGNITION ACTIVATORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |