Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273248 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CHRM2CHRM1CHRM3S1PR1 | |
| SCHEMBL7316819 | 0.81 | ALDH1A1 (0.41) | ALDH1A1PKM | |
| SCHEMBL7372638 | 0.79 | PREP (0.39) | ALDH1A1PREPNPC1SMN1; SMN2 | |
| SCHEMBL7321743 | 0.78 | F2 (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7316425 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CHRM2CHRM1CHRM3HTT | |
| SCHEMBL7374895 | 0.74 | CTSK (0.40) | PREPNPC1RAB9A | |
| SCHEMBL7313154 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CHRM2CHRM1CHRM3S1PR1 | |
| SCHEMBL8634379 | 0.72 | PREP (0.34) | PREPATM | |
| SCHEMBL8634381 | 0.72 | PREP (0.34) | PREPATM | |
| SCHEMBL8634383 | 0.72 | PREP (0.34) | PREPATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |