Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324905 | 1.00 | PREP (0.44) | PREPNPC1MEN1RAB9AKMT2A | |
| SCHEMBL7325890 | 0.98 | PREP (0.44) | PREPNPC1MEN1RAB9AKMT2A | |
| SCHEMBL7325895 | 0.98 | PREP (0.44) | PREPNPC1MEN1RAB9AKMT2A | |
| SCHEMBL9255056 | 0.81 | ACE (0.46) | HPGDSMN1; SMN2F2 | |
| SCHEMBL9569393 | 0.81 | ACE (0.46) | HPGDSMN1; SMN2F2 | |
| SCHEMBL10509504 | 0.81 | NPC1 (0.55) | PREPNPC1MEN1RAB9AKMT2A | |
| SCHEMBL10509497 | 0.81 | NPC1 (0.55) | PREPNPC1MEN1RAB9AKMT2A | |
| SCHEMBL7317218 | 0.81 | PREP (0.42) | PREPNPC1MEN1RAB9AKMT2A | |
| SCHEMBL7372638 | 0.81 | PREP (0.39) | PREPNPC1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL8636076 | 0.80 | FKBP1A (0.49) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | claimed |