Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191187 | 0.91 | BCHE (0.46) | BCHEKMT2AMEN1NPC1RAB9A | |
| SCHEMBL11595731 | 0.79 | CRHBP (0.49) | BCHEKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27034917 | 0.76 | BCHE (0.46) | BCHEKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29372916 | 0.76 | NPSR1 (0.66) | BCHEKMT2AMEN1NPC1RAB9A | |
| SCHEMBL19717911 | 0.76 | NPSR1 (0.66) | BCHEKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27773934 | 0.74 | NPSR1 (0.68) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL7591937 | 0.74 | BCHE (0.56) | BCHEKMT2AMEN1RAB9APOLB | |
| SCHEMBL9195795 | 0.73 | NPC1 (0.42) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL9195638 | 0.73 | ALDH1A1 (0.48) | BCHEKMT2AMEN1TP53NPSR1 | |
| SCHEMBL9196268 | 0.73 | MAPT (0.50) | BCHEKMT2AMEN1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123444-A1 | 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |