Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273317 | 0.91 | BCHE (0.48) | BCHEMEN1KMT2APOLBNPSR1 | |
| SCHEMBL9196268 | 0.82 | MAPT (0.50) | BCHEMEN1KMT2APOLBTDP1 | |
| SCHEMBL9195638 | 0.82 | ALDH1A1 (0.48) | BCHEMEN1KMT2ANPSR1TDP1 | |
| SCHEMBL9195795 | 0.82 | NPC1 (0.42) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL2678410 | 0.78 | SMN1; SMN2 (0.51) | MEN1KMT2APOLBNPSR1NPC1 | |
| SCHEMBL9192927 | 0.78 | ATM (0.52) | MEN1KMT2ANPSR1TDP1NPC1 | |
| SCHEMBL11595731 | 0.77 | CRHBP (0.49) | BCHEMEN1KMT2APOLBNPSR1 | |
| SCHEMBL19717911 | 0.76 | NPSR1 (0.66) | BCHEMEN1KMT2APOLBNPSR1 | |
| SCHEMBL29372916 | 0.76 | NPSR1 (0.66) | BCHEMEN1KMT2APOLBNPSR1 | |
| SCHEMBL9190580 | 0.76 | MAPT (0.49) | BCHEMEN1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443474-B1 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO (JP) | 1995-08-16 | — | — | EP | disclosed |
| US-5227395-A | ANTI-PLATELET AGGREGATING AGENT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5140041-A | Cognition activators, for treatment of Alzheimer's disease | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| EP-0443474-A2 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |