Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 7/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282036 | 0.87 | MMP2 (0.41) | ITGB3ITGA2BMMP2PPARAPPARD | |
| Hydrochloric Acid SCHEMBL7283263 | 0.87 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL7275831 | 0.86 | MMP2 (0.39) | MMP2MEN1KMT2AMMP3MMP1 | |
| SCHEMBL7275763 | 0.85 | KDM4E (0.41) | ITGB3ITGA2BMMP2PPARAPPARD | |
| SCHEMBL7282402 | 0.85 | MMP2 (0.43) | ITGB3ITGA2BMMP2PPARAPPARD | |
| SCHEMBL7283823 | 0.84 | MMP2 (0.45) | ITGB3ITGA2BMMP2PPARAPPARD | |
| SCHEMBL7276199 | 0.83 | HPGD (0.45) | ITGB3MMP2PPARAPPARDMEN1 | |
| SCHEMBL7273518 | 0.83 | ABCB1 (0.46) | ITGB3ITGA2BMMP2PPARAPPARD | |
| SCHEMBL7284836 | 0.82 | MMP2 (0.46) | MMP2PPARAPPARDMMP3HRH3 | |
| SCHEMBL7275504 | 0.82 | ABCB1 (0.45) | ITGB3ITGA2BMMP2PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |