Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283591 | 0.92 | KDM4E (0.40) | KDM4EMMP2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7276199 | 0.88 | HPGD (0.45) | KDM4EMMP2SMN1; SMN2ABCB1HPGD | |
| SCHEMBL7283772 | 0.87 | KDM4E (0.40) | KDM4EMMP2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7309719 | 0.87 | ITGB3 (0.52) | NPC1RAB9ASMN1; SMN2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7275004 | 0.87 | ITGB3 (0.52) | NPC1RAB9ASMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL7273375 | 0.85 | ITGB3 (0.44) | KDM4EMMP2SMN1; SMN2MMP3HPGD | |
| SCHEMBL7282036 | 0.85 | MMP2 (0.41) | MMP2MMP3HPGDPPARAPPARD | |
| SCHEMBL7272973 | 0.83 | HPGD (0.43) | KDM4ENPC1SMN1; SMN2ABCB1HPGD | |
| SCHEMBL7283823 | 0.82 | MMP2 (0.45) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL7284165 | 0.82 | MMP2 (0.42) | KDM4EMMP2SMN1; SMN2MMP3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |