Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 14/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7282768 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2BIRAK4CD274 | |
| SCHEMBL7280863 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BIRAK4FFAR1 | |
| SCHEMBL7283786 | 0.81 | ITGB3 (0.73) | ITGB3ITGA2BIRAK4FFAR1 | |
| SCHEMBL7285473 | 0.74 | ITGB3 (0.62) | ITGB3ITGA2BIRAK4FFAR1 | |
| SCHEMBL7273790 | 0.74 | ITGB3 (0.70) | ITGB3ITGA2BIRAK4FFAR1 | |
| SCHEMBL7272827 | 0.74 | ITGB3 (0.69) | ITGB3ITGA2BIRAK4 | |
| Hydrochloric Acid SCHEMBL7284326 | 0.73 | ITGB3 (0.48) | ITGB3ITGA2BIRAK4 | |
| Hydrochloric Acid SCHEMBL7281221 | 0.72 | ITGB3 (0.57) | ITGB3ITGA2BIRAK4 | |
| SCHEMBL7301919 | 0.70 | ITGB3 (0.72) | ITGB3ITGA2BIRAK4 | |
| SCHEMBL7272822 | 0.69 | ITGB3 (0.71) | ITGB3ITGA2BIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |