Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273458 | 0.88 | ITGB3 (0.44) | RPS6KA3 | |
| Hydrochloric Acid SCHEMBL7281884 | 0.87 | ITGB3 (0.43) | RPS6KA3 | |
| Hydrochloric Acid SCHEMBL8573867 | 0.87 | ITGB3 (0.43) | RPS6KA3 | |
| SCHEMBL7282163 | 0.85 | PTPN1 (0.37) | RPS6KA3HRH3ADRB2ADRB1PTPN1 | |
| SCHEMBL7281314 | 0.83 | RPS6KA3 (0.39) | RPS6KA3TSHRHRH3CYP11B1CYP11B2 | |
| SCHEMBL7273332 | 0.80 | CYP11B2 (0.51) | RPS6KA3TSHRHRH3CYP11B1CYP11B2 | |
| SCHEMBL7282680 | 0.80 | CYP11B2 (0.51) | RPS6KA3TSHRHRH3CYP11B1CYP11B2 | |
| SCHEMBL7274885 | 0.80 | LMNA (0.35) | RPS6KA3HRH3ADRB2ADRB1PTPN1 | |
| SCHEMBL7280894 | 0.79 | F2 (0.43) | — | |
| SCHEMBL7281654 | 0.78 | KMT2A (0.40) | HRH3ADRB2ADRB1HPGDPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |