Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 3/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278999 | 0.91 | OPRM1 (0.55) | TRHROPRM1 | |
| SCHEMBL7273117 | 0.85 | TRHR (0.47) | TRHRCAPN1 | |
| SCHEMBL7282889 | 0.84 | TRHR (0.46) | TRHR | |
| SCHEMBL9746806 | 0.83 | ACE (0.55) | TRHRACEOPRM1 | |
| SCHEMBL7276757 | 0.83 | TRHR (0.44) | TRHRACE | |
| SCHEMBL7271234 | 0.83 | OPRM1 (0.54) | TRHRACEOPRM1 | |
| SCHEMBL7280071 | 0.82 | OPRM1 (0.53) | TRHRACEOPRM1 | |
| SCHEMBL7280062 | 0.82 | OPRM1 (0.53) | TRHRACEOPRM1 | |
| SCHEMBL7273766 | 0.82 | TRHR (0.47) | TRHR | |
| SCHEMBL7271564 | 0.82 | TRHR (0.47) | TRHRCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | claimed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | claimed |
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |